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Laboratory studies demonstrate that ES2 peptides show 3-7 times more potent senolytic activity than FOXO4-DRI in both in vitro and in vivo experimental systems, while CPP-CAND demonstrates approximately 1.2-fold higher selectivity despite shorter peptide length

Gamma-glutamyl transpeptidase deficiency has been found in patients with CNS involvement and glutathionuria

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Glutathione plays a key role in the liver's detoxifying processes, and it also has powerful antioxidant capabilities

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