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ii) Mechanistic gaps: While numerous proteins and pathways have been implicated in ferroptosis, many studies focus on upstream events

doi: 10.3389/fphys.2019.00022 [DOI] [PMC free article] [PubMed] [Google Scholar] 341

A Benjamini-Hochberg FDR threshold of 0.01 marked significance

However, MitoQ's efficacy in altering disease progression in PD patients over 12 months was limited, likely due to insufficient brain penetration and severe dopaminergic deficiency [279]
