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10.1016/j.clnu.2020.01.011 113

Based on the available evidence, therapeutic interventions aimed at modulating the intestinal microbiomesuch as probiotics, prebiotics, synbiotics, and FMT, can be effective in combating obesity and promoting weight loss

The term porphyria is of Greek origin and meaning purplish pigment, relating to the color of porphyrins

Simultaneously, islet macrophages were closely associated with sympathetic fibres, expressed adrenergic receptors at high levels and shifted their cytokine production with adrenergic stimulation - in particular, when cultured with NA at high or low concentrations, macrophages were respectively polarized towards M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotypes, and this was attributed to the preferential activation of beta receptors at high NA concentrations (Christoffersson et al., 2020)

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