oxidised glutathione glucose 6 phosphate dehydrogenase defciency Biochemical role of G6PD enzyme in the cells [GHS: reduced glutathione; Glucose-6-Phosphate Dehydrogenase: Update and Analysis

Vetter, M

Further investigation leads to a diagnosis of tuberculosis

Liver, kidney, and spleen samples were sliced and stored at -80 C for further analysis of catalase activity (CAT), reduced glutathione (GSH), and superoxide dismutase (SOD)

To detect and filter blood samples of low quality, the Integrated Biobank of Luxembourg (IBBL), which processed the study samples, performed the following assays as part of its routine quality control: 1) Complete blood cell counting using an ABX Micros 60 Hematology Analyzer on a small aliquot of the whole blood before centrifugation, providing the following 6 parameters: White blood cell count (WBC), red blood cell count (RBC), hemoglobin (HGB), mean corpuscular volume (MCV), hematocrit (HCT), C-reactive protein (CRP)

From a toxicology standpoint, a pleiotropic, multi-pathway mechanism is a double-edged observation: it may explain the broad tissue tolerability seen so far, but it also widens the surface area of biology that a complete safety program would need to interrogate, because a molecule that touches many pathways has many pathways through which an unintended long-term effect could emerge