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Yamazhan M, Ertas IE, Kandiloglu G, et al

52 Pharmacotherapy The first specific treatment for obesity due to a single gene defect for leptin deficiency in the form of recombinant leptin therapy, which reduces appetite and increases satiety, resulting in weight loss, was first approved by the FDA in February 2014

Reduced appetite, nausea and vomiting

Therefore a provisional diagnosis of Oral melanotic maculae was made
Advances in mass spectrometry-based glycoproteomics
