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This cytokine modulation appears to be a key mechanism underlying its efficacy in models of inflammatory bowel disease, surgical wound healing, and systemic inflammatory injury

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Originally isolated from rabbit brains during sleep, DSIP functions as a central nervous system neuromodulator to improve sleep quality, enhance mood, and potentially reduce chronic pain

183 The results showed that the mean pain scores decreased from 7.1 to 1.8 on a numeric rating scale (NRS) at 1 month, and this effect was maintained at 6 months, although there was no change in mean T2 values