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Next, we discuss how the regulation of the Ras/Raf/MEK/ERK pathway activation by epigenetic modifications induces sorafenib resistance

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These limitations underscore the urgent need for more effective and safer therapeutic strategies (Hardy, 2025)

According to the National Center for Complementary and Integrative Health (NCCIH) at the NIH, melatonin is classified as a dietary supplement in the US meaning it is regulated far less strictly than pharmaceutical drugs by the FDA

In addition to skin benefits, glutathione promotes detoxification, immunological function, and overall wellness
