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In the 1960s, an initial endeavor was taken to implement the use of nanotechnology within the field of medicine, specifically at the esteemed academic institution of ETH Zurich, it is a Swiss public research university located in Zrich (133)

Immune cells use ROS to sustain their functions and need adequate levels of antioxidant defenses to avoid harmful effects caused by excessive ROS production, since accurate balance between ROS and intracellular antioxidants is essential for a normal function of the cell (Banjac et al., 2008

The strong protic base necessary to abstract the proton is a tertiary alkoxide that is generated from the hydroquinone form of vitamin K, through a mechanism involving the reaction with molecular oxygen, referred to as base strength amplification by oxidation [206]

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