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Although far less common, long-term increases in free fatty acids and reduced short-chain fatty acid production can precipitate myocardial insulin-resistance [102] while ketone bodies can promote cardiac scarring and cell senescence [103]

Therefore, the treatment goal should be to restore arginine to physiological levels, rather than reaching the level of an 'inflammatory cytokine storm' to support immune homeostasis (143,146,148)

CNE-1 and CNE-2 cells were kindly provided by A/Prof Shen Han Ming from the Department of Physiology, NUS

Emerging evidence indicates that the balance between beneficial and detrimental blue light effects is modulated by intensity, photoreceptor abundance, species-specific traits, and developmental context