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Description
Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin
Mitochondrial PDT involves targeting photosensitizers to the mitochondria, and when light excites the photosensitizers, the photosensitizer undergoes an energy transfer to produce a lot amount of ROS
However, research has not confirmed they are safe or effective for this purpose
Spinal Cord 1997;35:171-5
Furthermore, mitochondrial damage is present early in disease course in TDP-43 A315T mice and increases motor neuron vulnerability (Gautam et al., 2019), consistent with dysregulation of the redox system early in neurodegeneration
