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doi: 10.1074/jbc.M602802200
Age is a common factor, but not a specific cause

Improvement in electroporation efficiency for Lactobacillus plantarum by the inclusion of high concentrations of glycine in the growth medium

The core clinical value of this drug class lies in their use as adjuncts to L-DOPA, significantly prolonging patients' "on" time, shortening "off" time, and potentially reducing the total daily dose of L-DOPA

[Abstract]2022 Apr;42(4):694-705