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Therefore, the absence of hematological abnormalities should not exclude the diagnosis of SCD

In a study conducted by Jimenez and Downs (2020) [75], the authors measured oxidative stress parameters either in plasma or in erythrocytes (depending on a parameter) from domestic dogs and wild canids of various ages and body sizes

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Senescent fibroblasts and endothelial cells, through the secretion of SASPparticularly PDGF-Apromote an increase in myofibroblast numbers at wound sites, which positively affects wound healing [141]

stimulation of iNOS and NO release from trigeminal ganglion glial cells involves mitogen-activated protein kinase pathways