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In addition, protein products of these genes play crucial roles in the meiotic phases of spermatogenesis and are present at high levels in spermatocytes (96, 111, 112)

AMPK can be thought of as a key contributing factor of HIF-1 functions in response to H 2 O 2 , and it may also play a role in the complex HIF-1 regulatory mechanisms (Figure 4) [57]

Researchers have also identified novel regulators of the Wnt/-catenin pathway, such as Twa1, 71 TMEM59, 308 GPR124, and Reck

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