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ERGO inhibited activities of HNMT in the mouse brain cytosol and recombinant human HNMT (rhHNMT) in a concentration-dependent manner (Fig

Similarly, a gene set enrichment analysis (GSEA) performed on the same dataset, which could reveal subtler alterations, did not show significant skewing in the rank distribution of GABAergic interneuron markers ( p = 0.187) and differentiation genes ( p = 0.884) (Fig

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