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Chronic inflammation also plays a significant role in cardiovascular diseases

[DOI] [PubMed] [Google Scholar] 46.Jin Y, Blikslager AT

These infections, often due to persistent pathogens such as Pseudomonas aeruginosa , Haemophilus influenzae , and Streptococcus pneumoniae , disrupt the normal airway environment [6]
This includes the production and recycling of antioxidants like glutathione

These mediators can compromise the integrity of the BBB, allowing the entry of viruses and cytokines into the CNS and activating brain immune cells, resulting in neuroinflammation [48,51,52,53]
