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Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

Chiodini PG, Liuzzi A, Botalla L, Cremascoli G, Silvestrini F
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Mitochondria morphological changes are associated with dysfunction and altered energy metabolism, whereby adenosine triphosphate (ATP) production is insufficient to maintain the Na+/K+-ATPase neuronal activity, which leads to massive calcium (Ca +2 ) influx followed by glutamate toxicity [24]

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