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The effect of L-Carnitine and proinflammatory cytokines in the development of nonalcoholic steatohepatitis
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10.3390/ijms20071800 111 QureshiM
Simultaneously, physical activity initiates mitochondrial biogenesis (mediated by peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1), enhances mitophagy, maintains the balance between mitochondrial fusion and fission, and optimizes electron transport chain efficiency, which collectively mitigates ROS production and safeguards the functionality of both muscle and endothelial cells (74)
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