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Circulating antibody to transcobalamin II causing retention of vitamin B12 in the blood

(PubMed) Quadri P, Fragiacomo C, Pezzati R, Zanda E, Tettamanti M, Lucca U

Vitamin B12 is necessary for the production of red blood cells, which help carry oxygen throughout the body

Various preclinical studies conducted over the past few years have found that high dosages of vitamin C could act as an adjuvant prooxidative agent, primarily in chemotherapy and/or radiotherapy of glioblastoma cells [78, 82, 84, 86]

We propose testing intralesional or intraperitoneal depot systems, as well as nanoparticle and liposomal carriers engineered to concentrate drug within pelvic lesions while limiting distribution to hematopoietic and hepatic tissues (9799)