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Although there was no effect on sperm motility or sperm density in the epididymis, there was a significant increase in the percentage of abnormal sperm in mice consuming 1.78 times the MHDD (based on a body surface comparison) and there was a reduction in the number of mating pairs producing a fifth litter at this dose, suggesting the potential for cumulative toxicity with chronic administration of acetaminophen near the upper limit of daily dosing

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The height of the Gauss curve corresponds to the DEM/DCF concentration

[DOI] [PubMed] [Google Scholar] 3.Rabinstein A.A., Shulman L.M

BPC-157 is commonly studied in the context of tissue signaling, angiogenesis, gastric biology, nitric oxide modulation, and musculoskeletal tissue research in preclinical models