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Among the agents that mediate their effects through S -glutathionylation, NOV-002 has been most extensively studied, with a phase III trial (NCT00347412) completed in advanced NSCLC [104], and data available from phase II trials in breast and ovarian cancers [105]

In the context of PD, FUS, particularly through high-intensity focused ultrasound (HIFU), has shown significant promise

Wang Y, Chen Z, Luo J, Zhang J, Sang AM, Cheng ZS, Li XY (2023) Salidroside postconditioning attenuates ferroptosis-mediated lung ischemia-reperfusion injury by activating the Nrf2/SLC7A11 signaling axis

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10.1002/ijc.31300 90
