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Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock

doi: 10.1016/j.etap.2014.04.028 305 PrabakaranDAshokkumarN

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In the pre-specified week-72 analysis of part 1, 62.9% of semaglutide-treated participants achieved resolution of steatohepatitis without worsening of fibrosis versus 34.3% with placebo (estimated difference ~28.7 percentage points), and unlike the earlier phase 2 36.8% achieved improvement in liver fibrosis without worsening of steatohepatitis versus 22.4% with placebo (estimated difference ~14.4 points