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Like other toxic heavy metals, Cd is greatly concentrated in the upper levels of food chain (Jrup and Akesson, 2009)

It was found that the effective chemopreventive agents derived from plants that can inhibit the activation of PI3K/Akt/mTOR pathway provide a rationale strategy to overcome the incidence of many physiological and pathological conditions, such as cell proliferation, differentiation, metabolism, angiogenesis and survival in cancer cells

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Syringic acid mitigates myocardial ischemia reperfusion injury by activating the PI3K/Akt/GSK-3 signaling pathway

High-fiber, polyphenol-rich diets foster beneficial bacteria like Bifidobacterium and Lactobacillus, which suppress procarcinogenic species and lower inflammation