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Extra vitamin B12 can be stored in the liver, and only small amounts are lost through your urine, sweat, or stools each day

Scratching causes mechanical mast cell degranulation, releasing additional histamine and creating a vicious itch-scratch cycle
Vitamin B12 functions as a cofactor for enzymes that catalyse the conversion of homocysteine into methionine, which is then converted into intermediates that are used in the synthesis of pyrimidine bases of DNA
