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focal melanotic macule a at the wet–dry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

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Ceramides are sphingosine molecules with a fatty acid tail attached to the amino group

focal melanotic macule a at the wetdry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

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focal melanotic macule a at the wetdry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

Psoriasis treatments typically involve topical creams or ointments, phototherapy, oral medications, and biologic injections, says Allison-Fecteau

focal melanotic macule a at the wetdry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

The mitochondrial connection: CoQ10 is a fat-soluble antioxidant found in virtually every cell in the body, but it plays a particularly critical role in mitochondria the cellular powerhouses

focal melanotic macule a at the wetdry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

FM has an inflammatory component due to elevated levels of inflammatory cytokines such as IL-6 and decreased levels of anti-inflammatory cytokines like IL-10 [18]

focal melanotic macule a at the wetdry line of the lower lip. b Melanotic Differential Diagnosis of Pigmented Lesions

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