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Figure 5 Figure 6 3.5.3 Significantly different metabolites In order to visualize the expression differences of intestinal samples and metabolites among different samples, this study performed hierarchical clustering of the expression levels of all significant differential metabolites among the top 50 significant differential metabolites according to VIP sorting

RSV-treated mice exhibited significantly fewer and smaller polyps compared to the control group, alongside reduced histological evidence of epithelial damage and lower proliferation of intestinal epithelial cells (45)

& Fatollahierad, S

Moreover, metformin induces cell cycle arrest and apoptosis through the Bcl-2-family of proteins in primary human ovarian carcinoma cells, isolated from ascitic fluid or omental metastases (Liu et al., 2018)

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