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The participants with previously diagnosed with viral hepatitis (ICD-10: B15-18) (n = 254,831) or liver cirrhosis (ICD-10: K74) (n = 9,902) before 2009 were excluded

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7.1 Probiotic-driven immune activation: enhancing host defense A diverse range of probiotic strains exhibit potent immunostimulatory properties, strengthening host defenses by enhancing pathogen recognition and clearance (218)