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Dysbiosis in CKD has been touted to be due to slow intestinal transit time, delivery of undigested protein to the colon, decreased dietary fiber intake, iron therapy, frequent use of proton pump inhibitors and antibiotics [43]

Comparison of the conformation of amyloid beta (128) peptide fragment with its Lys28 N-acetyl derivative Soc Neurosci Abstr 1997

Regarding its anti-inflammatory and anti-androgenic effects, vitamin D potentially diminishes advanced glycation end products (AGEs)-induced androgen synthesis via downregulating the expression of the receptor for advanced glycation end products (RAGE) and further lowers pro-inflammatory cytokine levels via inhibiting the activity of the phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) signaling pathway, consequently improving glucose homeostasis (47)