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One of the main components of amyloid plaques is the amyloid -peptide (A), generated by the proteolytic cleavage of the amyloid precursor protein (APP) by - and -secretases

It is characterized by cell shrinkage, chromatin condensation, DNA fragmentation, and the formation of membrane-bound apoptotic bodies, which are subsequently cleared by macrophages without triggering a strong inflammatory response

Glycine is one of the major amino acids that forms collagen and is pivotal for collagen synthesis (Hamanaka and Mutlu, 2021)

[DOI] [PubMed] [Google Scholar] 31.Crosbie EJ, Kitson SJ, McAlpine JN, Mukhopadhyay A, Powell ME, Singh N

In summary, our data implicate a novel mechanism protecting against liver steatosis via an oxidative stress adaptive response that activates the AMPK pathway