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Clinicians: persistent cytokine signaling, immune cell infiltration, and progressive interstitial fibrosis impair glomerular and vascular function
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To this end, a key issue concerns the choice of discriminating clustering factors

This treatment is especially beneficial when rapid results are neededsuch as for severe dehydration, infections requiring antibiotics, or when oral medications arent an option

Cell 132 , 631644 (2008)
