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Such a candidate treatment may constitute part of an LPS reduction therapy that could provide evidence to support related theories such as the endotoxin theory of AD (Brown and Heneka, 2024)

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(2017) Sci Rep 7 : 7897-7897 PubMed: 28801553 Search on PubMedSearch on PubMed Central DOI: Primary Citation Related Structures: 5I9K, 5IA9 PubMed Abstract: Microsomal glutathione transferase 1 (MGST1) is a detoxification enzyme belonging to the Membrane Associated Proteins in Eicosanoid and Glutathione Metabolism (MAPEG) superfamily

Integrating the latest genomics (transcriptomics), proteomics and lipidomics of pro-inflammatory and pro-resolution eicosanoid and related PUFA production should lead to new insights on infection and inflammation