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A second propylamine residue from dcAdoMet is added to spermidine producing spermine by the enzyme spermine synthase encoded by the SMS gene (also known as SPMSY)

[65] A 2018 review by the Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment (COC) concluded that there is "insufficient evidence to draw any firm conclusions as to whether exposure to dietary IGF1 is associated with an increased incidence of cancer in consumers"

Science 350:10691101

PCC6803, a MerA-like enzyme that functions in mercury and uranium reduction was shown to be redox-controlled by S -glutathionylation (Marteyn et al., 2013)