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For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials
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[DOI] [PubMed] [Google Scholar] 125.Werler MM, Mitchell AA, Hernandez-Diaz S, et al

The absence of upper motor neuron involvement in the present case may reflect either early-stage disease or the heterogeneous progression of vitamin B12-related neuropathy
In the REDEFINE 1 trial, CagriSema produced 20.4% body weight loss over 68 weeks