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Interestingly, more blast phase CML, a more advanced phase biologically more similar to acute leukemia, is relatively insensitive to the GVL effect of DLI, further underscoring the so far undefined contribution of disease biology to success or failure of GVL (46, 59, 60)

It has a smaller molecular weight (15 kDa) compared to the full-length antibody daratumumab, exhibits rapid uptake in tumors with high tumor/background ratios and undergoes rapid metabolism in vivo

Probiotics have also reduced abdominal pain in older children

When peptides influence body composition or insulin sensitivity, they may interact negatively with weight loss therapy plans or nutritional supplements