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They regulate local intestinal function and systemic metabolism through multiple mechanisms (77)
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A KD switches primary energy consumption from glucose to ketones, bypassing the need to utilize the defective complex I and instead primarily utilizing complex II, which may help restore appropriate mitochondrial function and energy production (37)

Cellular Repair: Promotes DNA repair and synthesis, aiding in the maintenance of healthy cells

However, ebselen and ebsulphur completely restore dimer formation affinity to a wild-type level, K d 163 and 234 nM, respectively (Fig
