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This dual mechanism, reduced intake plus increased expenditure, explains why the Phase 2 data showed such dramatically higher weight loss percentages than any dual agonist trial

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When looking at the percentage of participants that dropped out of the trial due to adverse effects, 2-6% of patients in the cagrilintide group discontinued treatment early while 7% of the participants receiving liraglutide discontinued treatment early, These findings were in comparison to only 3% of test subjects from the placebo group that discontinued treatment due to adverse events [1]

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