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David Reply I would like to know if my wife has a fighting chance she has stage 4 colon cancer and after surgery they said she has 21 spots in her liver she,s been on chemo for 1year and 9 months they had gave her 2 years to live.she still looks the same the only thing is she lost her hiar,and very stressed,sometimes I wonder if they missed diagnoused her.recently they started a stronger chemo,they said the cancer is not responding to the chemo she was getting,now I,m worried maybe they want to put her down faster,i am very frusterated,I even googled the doctors name and found that there is not too much good to say about her

found that in pancreatic cancer patients, the expression of ubiquitin-specific protease 8 (USP8) is increased, and USP8 stabilizes NRF2 expression by deubiquitinating K48-linked polyubiquitin chains on NRF2