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a decrease of hepatic lipid accumulation by activating the autophagy-mitochondrial pathway in human hepatoma cells was reported [183]
In addition, of eight antibodies that were effective agonists for the GHR/G-CSFR hybrid, only one antibody acted as an agonist with weak activity on full-length GHR, suggesting that receptor dimerization alone is not sufficient for activation (46)
Picard et al
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