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Thus, therapeutic agents that reduce the activation of STAT1 and/or suppress STAT3 may induce an anti-inflammatory effect by promoting the polarisation of M1 to the M2 phenotype [353]

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46 (3), e13635

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Although further studies on secreted exosomal SELENOP are required, the exosomal transport of selenoprotein through BBB to neuronal cells might be an alternative route for Se delivery into the brain