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Depletion of endogenous GSH sensitizes cells to cuproptosis, whereas GSH supplementation mitigates copper-induced proteotoxic stress 164,168

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2) in Brazil, APL is treated in specialized centers and non-specialized centers, and the incorporation of ATO is relatively new

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coli NEBExpress was first transformed with the pKD46 plasmid and then typically grown in 2 L Terrific Broth (TB) medium supplemented with 100 g/mL Amp at 30 C in the presence of 0.2 % (w/v) arabinose to induce expression of the Red genes

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A full medical assessment is carried out to identify any contraindications or medication interactions.

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