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However, endothelial dysfunction or endothelial cell death can cause vascular barrier disruption, vasoconstriction and diastolic dysfunction, vascular smooth muscle cell proliferation and migration, inflammatory responses, and thrombosis, which are closely associated with the progression of several diseases, such as atherosclerosis, hypertension, coronary atherosclerotic heart disease, ischemic stroke, acute lung injury, acute kidney injury, diabetic retinopathy, and Alzheimers disease

Due to the small volume of blood collected, we were unable to separate the blood plasma from the erythrocytes

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leucocephala seed protein isolates with relatively low mimosine levels through isoelectric precipitation of seed kernel proteins