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Use the product with caution in cardiac animals
It does appear to have some activity at other receptors, which may account for its side effects (for example its tendency to cause low blood pressure on standing may be due to its blocking effect on adrenergic alpha1 receptors)

Ryan, C
And they are focused on patients and on the real world

Therapeutic strategies aimed at reprogramming microglia toward neuroprotective phenotypes offer a novel and potentially transformative approach, particularly in early disease stages when neuronal loss may still be preventable
