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However, their clinical translation is impeded by their low bioavailability, poor stability, and inability to cross the BBB 25
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doi: 10.1016/S0959-4388(00)00208-7
Folate insufficiency was one of these three variables that had the most impact on the serum tHcy levels, followed by MTHFR C677T and vitamin B12 deficiency (in decreasing order of impact) [48]
doi: 10.3390/foods10030596
