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Huang et al 45 also conducted research on delivery of TP and developed Pluronic F127/P123 NPs (TP-FPNPs) with folate as a targeting moiety, modified with the toxic drug TP

The main drivers of ferroptosis are the inactivation of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and the induction of ROS, particularly lipid ROS
