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Another important issue is the damage caused by cryopreservation of sperm as part of assisted reproductive technology

In acid sphingomyelinase knock-out mice, which mimic a neurovisceral acid sphingomyelinase deficiency (ASMD) characterized by cellular accumulation of sphingomyelin, the effects of a choline-free diet decreased the activation of liver macrophages and microglia, but it did not significantly alter sphingomyelin levels due to compensatory mechanisms involving methionine metabolism (101)

a high-quality B-complex supplement or multivitamin supplement can also help

Association No

doi: 10.1016/S0015-0282(02)03294-6 [DOI] [PubMed] [Google Scholar] 61