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However, the activities of GPXs attain a plateau with Se intakes that are lower than those required for plateauing the levels of selenoprotein P, which is considered the most informative biomarker of the functional Se status (45)

Mitochondrial calcium homeostasis in the pathology and therapeutic application in friedreich's ataxia

Role of Transglutaminase Antibodies : The presence of these antibodies indicates an autoimmune reaction against gluten, which causes inflammation and damage in the brain, contributing to ataxia symptoms such as impaired coordination and balance

Compared to placebo, the treatment with intramuscular acetyl-l-carnitine significantly reduced weekly mean pain on the VAS, whilst during the open-label part of the study, oral acetyl-l-carnitine improved symptoms in the entire cohort, with no safety issues [81] (Table 2)