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But theres another important piece of the puzzle you might not hear about as often: detoxification

ROS are primary effectors of cytotoxicity induced by treatment with anti-cancer drugs

(PubMed) Carroll D, Ring C, Suter M, Willemsen G

Moreover, the protective effects of betaine on the liver may involve intergenerational communication between the liver and brain, such as regulating brain phospholipid metabolism (103)

Age- and sex-related differences of organic anion-transporting polypeptide gene expression in livers of rats
