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While in principle this condition leads to higher signal at any photon arrival time, higher sensitivity, and better spatial resolution 45 , in practice the benefits must be weighted against the stronger impact of the IRF on the detected signal due the the overwhelming burst of early photons

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Animal experiments, cellular experiments, reviews and meta-analyses related to ARHL were provided by each author and are discussed uniformly

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Further studies demonstrated that the iron chelator clioquinol effectively inhibits fibroblast activation, including cell proliferation, myofibroblast differentiation, pro-inflammatory cytokine secretion, and migratory capacity, thereby attenuating bleomycin-induced pulmonary fibrosis in mice (Zhu et al., 2021)