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Warning And Precaution: Neksium 40 mg Injection can worsen the conditions like: Allergy Kidney/ Liver disease You must not take this medicine if you are pregnant, planning to conceive or breastfeeding You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness You must drink sufficient amount of water with this medicine You must take adequate dietary intake of calcium & magnesium or their supplements as prescribed by your doctor as long-term use can cause weak bones & deficiency of minerals such as magnesium You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, and electrolyte levels during treatment with this medicine Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions

[DOI] [PMC free article] [PubMed] [Google Scholar] 311.Geraldes, P

Potential Benefits: STEP trials (n=1961) demonstrated approximately 15% body weight reduction over 68 weeks Reduces HbA1c 1.52% in diabetic patients Well-established safety profile Suggested Clinical Dosing Range: Titrated from 0.25 mg to 2.4 mg weekly subcutaneous Dosing is individualized and determined by a qualified medical provider

Abdo et al., 2021[1])

Elevated MMA levels in patients with vitamin B12 deficiency can contribute to myelin damage (myelopathy) and, consequently, peripheral and autonomic neuropathy ( Cobalamin deficiency can lead to neurological manifestations such as progressive axonal demyelination, impaired peripheral and sensory nerve function, areflexia, loss of proprioception and vibration sensitivity, and subacute combined spinal cord degeneration (70)