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A randomized, double-blind, placebo-controlled trial in 28 older women (ages, 65-70 years) found no effect of L-carnitine supplementation (1.5 g/day for 24 weeks) on serum pro-inflammatory cytokine concentrations, body mass and composition (lean [fat-free] mass and skeletal muscle mass), or measures of skeletal muscle strength (123)

RSD for instrumental system precision was 0.056, 0.031 (first day) 0.052, 0.023 (second day) for retention time and 0.872, 0.987 (first day) 0.882, 0.977 (second day) for area correspond to L-lysine hydrochloride and LCLT, respectively

For a more detailed explanation of stimulant-free fat metabolism support, read our guide on L-Carnitine for weight loss and fat metabolism

What distinguishes acetyl-L-carnitine from standard L-carnitine is the acetyl group attached at the 3-position oxygen, which increases lipophilicity and allows ALCAR to cross the blood-brain barrier more effectively than L-carnitine [5][6]

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