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Melatonin reduces lung oxidative stress in patients with chronic obstructive pulmonary disease: a randomized, double-blind, placebo-controlled study

For two of these drugs, risperidone and venlafaxine, the active metabolites (paliperidone and desvenlafaxine, respectively) were marketed as drugs in their own right several years after the parent drugs were marketed

doi: 10.1016/S1470-2045(18)30242-0 76 Bonfim-SilvaRSalomoKBPimentel TVC deAMenezes CCB deOPalmaPVBFontesAM

J., Ma, Q

The activation of p38 and ERK1/2 by AGEs in human coronary artery endothelial cells (HCAECs) increases oxidative stress and decreases eNOS expression, which in turn causes endothelial dysfunction [36]
